10 Powerful Dihydromyricetin (DHM) Benefits

dihydromyricetin benefits DHM

Dihydromyricetin, also abbreviated as DHM, is a flavonoid extracted from the Japanese Raisin Tree and other plant species. It has traditionally been used to treat liver disease and hangovers, but studies have shown that it also has numerous other benefits and positive effects on overall health.

In this article, we will discuss the benefits of Dihydromyricetin (DHM) and why you should consider supplementing Dihydromyricetin (DHM).


10 Powerful Dihydromyricetin (DHM) Benefits

Dihydromyricetin is a strong flavonoid and antioxidant. Discover these 10 powerful Dihydromyricetin (DHM) benefits:

1. Boost antioxidants to fight oxidative stress

Dihydromyricetin (DHM) is a flavonoid compound that has been shown to have antioxidant properties. In vitro studies have shown that DHM can scavenge free radicals and protect cells from oxidative stress. It is possible that DHM can help to protect the body against age-related damage and chronic diseases.¹

Antioxidants are beneficial because they neutralize free radicals, which can damage and destroy cells. Free radicals are a natural byproduct of chemical reactions in the body.²

Dihydromyricetin is a flavonoid found in a variety of plants such as Japanese Raisin Tree (or Hovenia Dulcis) and shown that it is high in antioxidant levels. Supplementing Dihydromyricetin can help neutralize free radicals and reduce the risk of oxidative stress.

2. Acts as a powerful anti-inflammatory

DHM is a potent anti-inflammatory due to its ability to inhibit the release of inflammatory cells called cytokines.

The results of a study show that DHM treatment effectively inhibited the number of inflammatory cells, including eosinophils, macrophages, lymphocytes, and neutrophils, in the mouse.³

This is important because inflammation contributes to many diseases and health conditions including cancer, autoimmune diseases, and atherosclerosis.

3. Enhances athletic performance

Dihydromyricetin (DHM) is an antioxidant that may help improve physical endurance and exercise activity.

The study found that DHM improved physical performance under simulated high-altitude conditions. DHM protected mitochondrial biogenesis and modulated mitochondrial dynamics in skeletal muscle cells.⁴

4. Hangover protection

One of the more popular uses, Dihydromyricetin (DHM) is shown to have positive effects when drinking alcohol to help hangovers. 

DHM has been shown to help prevent the development of hangover symptoms, improve the quality of sleep, and reduce the amount of time it takes to recover. 

Research shows that DHM can significantly reduce hangover symptoms, in part due to its ability to inhibit alcohol-induced acetaldehyde accumulation. Acetaldehyde is a metabolite of alcohol whose toxicity is thought to be responsible for many hangover symptoms.⁵

These studies suggest that DHM may be able to minimize the negative effects of drinking on the liver by helping the enzymes, alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH), responsible for breaking down acetaldehyde.⁶

5. Improves your mood, reduces anxiety and stress

DHM (dihydromyricetin) is an antioxidant that can help with mood, depression, and anxiety.

DHM has been shown to reduce stress hormones in the body by reducing cortisol levels (the stress hormone).⁷ Cortisol is released during times of physical or emotional stress, and chronic high levels can lead to adrenal fatigue.⁸

6. Protects the liver.

Dihydromyricetin is a compound found in certain plants and has been shown to improve liver function and protect the liver. For example, dihydromyricetin has been found to help prevent acetaminophen-induced hepatic injury.⁹

One potential benefit of dihydromyricetin that is not well known is that it can help prevent acetaminophen-induced hepatic injury. Acetaminophen is a common pain reliever and over-the-counter medication that can cause liver damage if taken in high doses or for a long period of time. Dihydromyricetin has been found to help protect the liver against this damage, suggesting that it may be a useful supplement for those who take acetaminophen regularly.

7. DHM can help to improve cognitive function and memory.

Dihydromyricetin is a natural compound that has been shown to improve cognitive function and memory. It is believed to work by activating the brain's hippocampus, which is responsible for memory formation and recall. Which again also impoves anxiety. 

Dihydromyricetin has been shown to improve cognitive function and memory. It is believed to work by activating the brain's hippocampus, which is responsible for memory formation and recall. Which again also impoves anxiety. In addition, dihydromyricetin has been found to help improve nerve function and protect the brain from damage caused by inflammation. Taken together, these findings suggest that dihydromyricetin may be a useful supplement for those who are struggling with cognitive impairment or memory loss.¹⁰

8. Improve non-alcoholic fatty liver disease.

Dihydromyricetin (DHM) is a natural compound that has been shown to improve non-alcoholic fatty liver disease (NAFLD). NAFLD is a condition in which the liver becomes enlarged and contains excessive amounts of fat. DHM has been shown to help reduce inflammation and improve liver function.¹¹

9. DHM Dihydromyricetin can help improve sleep quality.

Dihydromyricetin has been shown to improve sleep quality by interacting with GABA-A receptors especially when drinking alcohol.¹² This interaction is thought to help relax the mind and body, leading to a more restful sleep. In addition, DHM has been found to improve nerve function and protect the brain from damage caused by inflammation. Taken together, these findings suggest that DHM may be a useful supplement for those who are struggling with sleep quality.¹³

10. DHM improves brain function via GABA receptors.

Preliminary studies suggest that it may help the brain related to improving GABA function. GABA is a neurotransmitter that is important for regulating nerve cell activity and is believed to play a role in cognitive function and sleep.¹⁴

GABA helps you sleep, feel less stressed, and have a good mood. GABA also helps control muscle tone.

People with low GABA activity may have problems such as anxiety, chronic stress, depression, difficulty concentrating, and memory problems. They may also have muscle pain, headaches, and difficulty sleeping. 

DHM can help keep GABA in check.

Best DHM Supplement

best DHM supplement
Zaca Chewables are the best DHM supplement available on the market. Made with only pure quality ingredients including Hovenia Dulcis extract containing the potent DHM flavonoid. Feel all the benefits and boost your health in a natural way with DHM. Formulated in a 1100mg chewable tablet that you can take before bed or when you need it most. Try our DHM supplement today and feel better faster. 



What is dihydromyricetin?

What is DHM? Dihydromyricetin, or abbreviated as DHM, is a natural chemical found in and extracted from a Japanese raisin tree, also called Hovenia Dulcis. DHM is a natural compound that has been used in Traditional Chinese Medicine for centuries to treat a variety of conditions. It has also been used for hundreds of years to cure hangovers. Recent studies have shown that DHM can also have a number of benefits for the body.

Where to buy dihydromyricetin?

DHM is available as a dietary supplement, and although more rare to find in products, it can be purchased online or in some health food stores. Zaca provides DHM within its chewable, containing Japanese Raisin in which DHM is a flavonoid compound extract of.

Does dihydromyricetin work?

If you want social proof if dihydromyricetin (DHM) works, and what customers experience, we'd recommend reading throught the customer reviews of dihydromyricetin Zaca chewables on Amazon.

Can dihydromyricetin help Asian Flush?

Dihydromyricetin can help with Asian flush by helping to detox alcohol and other toxins.

Asian flush (also known as Asian glow or alcohol flush reaction) is a condition in which an individual's face or body experiences flushes, redness or blotches as a result of an accumulation of acetaldehyde. Acetaldehyde is a byproduct of the from your body breaking down alcohol. The syndrome is most commonly seen in those with an Asian heritage that consume alcohol. It is caused by an inherited deficiency in the enzyme aldehyde dehydrogenase, which breaks down acetaldehyde. 

Dihydromyricetin (DHM) has been shown to dramatically reduce the symptoms and damage caused by acetaldehyde, a toxin in alcohol that causes Asian flush. By taking DHM along with your drinks, you can help prevent this toxic buildup and enjoy drinking again.¹⁵

Dihydromyricetin good for alcohol or as a novel anti-alcohol intoxication medication?

Recently, DHM has been studied for its potential use as an anti-alcohol intoxication medication.¹⁶ So far, research has shown that DHM can help to reduce alcohol intake and improve alcohol detoxification, and the study considered Dihydromyricetin (DHM) as a therapeutic candidate. While more research is needed to confirm these findings, it is exciting to think about the potential benefits of DHM for alcohol abuse and addiction treatment.

Dihydromyricetin pills or dihydromyricetin tablets?

Dihydromyricetin pills or dihydromyricetin tablets, which is better? If you want to use it as a dietary supplement it comes down to personal choice. Although the concentration of dihydromyricetin in pills is relatively high, chewables tablets like Zaca can be the most convenient to take on-the-go, without the hassle of swallowing with water.

The more important factor is finding the best source of DHM, making sure it comes from a high quality extract of Japanese Raisin (Hovenia Dulcis).

Want to buy the best extract of dihydromyricetin (DHM)? Try our dhm-infused Recovery Chewables!






1. Preclinical Research of Dihydromyricetin for Brain Aging and Neurodegenerative Diseases
2. Dihydromyricetin Protects the Liver via Changes in Lipid Metabolism and Enhanced Ethanol Metabolism
Anti-inflammatory effects of dihydromyricetin in a mouse model of asthma
4. Dihydromyricetin improves physical performance under simulated high altitude
5. Hangover drug shows wider benefits
6. Natural Products for the Prevention and Treatment of Hangover and Alcohol Use Disorder
7. Social Isolation Induces Neuroinflammation And Microglia Overactivation, While Dihydromyricetin Prevents And Improves Them
8. Social isolation induces neuroinflammation and microglia overactivation, while dihydromyricetin prevents and improves them
9. Dihydromyricetin alleviates acetaminophen-induced liver injury via the regulation of transformation, lipid homeostasis, cell death and regeneration
10. Dihydromyricetin ameliorates memory impairment induced by acute sleep deprivation
11. Dihydromyricetin Ameliorates Nonalcoholic Fatty Liver Disease by Improving Mitochondrial Respiratory Capacity and Redox Homeostasis Through Modulation of SIRT3 Signaling
12. Chinese herbal flavonoid shows hangover busting potential
13. Using Dihydromyricetin for Alcohol Withdrawal and Hangovers
14. 3 Amazing Benefits of GABA
15. The Alcohol Flushing Response: An Unrecognized Risk Factor for Esophageal Cancer from Alcohol Consumption
16. Dihydromyricetin As a Novel Anti-Alcohol Intoxication Medication